The Past, Present and Future of Heart Transplantation

被引：82

作者：

Kim, In-Cheol ^{[1
]}

Youn, Jong-Chan ^{[2
]}

Kobashigawa, Jon A. ^{[3
]}

机构：

[1] Keimyung Univ, Dongsan Med Ctr, Div Cardiol, Daegu, South Korea

[2] Hallym Univ, Dongtan Sacred Heart Hosp, Div Cardiol, Coll Med, 7 Keunjaebong Gil, Hwaseong 18450, South Korea

[3] Cedars Sinai Smidt Heart Inst, Div Cardiol, 127 S San Vicente Blvd,Third Floor Cardiol A3107, Los Angeles, CA 90048 USA

来源：

KOREAN CIRCULATION JOURNAL | 2018年 / 48卷 / 07期

基金：

新加坡国家研究基金会;

关键词：

Heart transplantation; History; Current practice; Forecasting; Heart failure; ANTIBODY-MEDIATED REJECTION; CARDIAC ALLOGRAFT VASCULOPATHY; MYCOPHENOLATE-MOFETIL MMF; 2013 ACCF/AHA GUIDELINE; ASSOCIATION TASK-FORCE; LUNG TRANSPLANTATION; INTERNATIONAL SOCIETY; INTRAVASCULAR ULTRASOUND; CONSENSUS CONFERENCE; WORKING FORMULATION;

D O I：

10.4070/kcj.2018.0189

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart transplantation (HTx) has become standard treatment for selected patients with end-stage heart failure. Improvements in immunosuppressant, donor procurement, surgical techniques, and post-HTx care have resulted in a substantial decrease in acute allograft rejection, which had previously significantly limited survival of HTx recipients. However, limitations to long-term allograft survival exist, including rejection, infection, coronary allograft vasculopathy, and malignancy. Careful balance of immunosuppressive therapy and vigilant surveillance for complications can further improve long-term outcomes of HTx recipients.

引用

页码：565 / 590

页数：26

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