The ascorbate transporter SVCT2 to target microglia-dependent inflammation

被引:4
|
作者
Portugal, Camila C. [1 ,2 ]
Socodato, Renato
Relvas, Joao B.
机构
[1] Univ Porto, Inst Invest & Inovacao Saude, Oporto, Portugal
[2] Univ Porto, IBMC, Oporto, Portugal
关键词
caveolin-1; NF-kB; Src kinase; ROS; neuroinflammation; VITAMIN-C;
D O I
10.18632/oncotarget.22306
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:99217 / 99218
页数:2
相关论文
共 50 条
  • [1] Macrophage differentiation increases expression of the ascorbate transporter (SVCT2)
    Qiao, Huan
    May, James M.
    FREE RADICAL BIOLOGY AND MEDICINE, 2009, 46 (08) : 1221 - 1232
  • [2] Macrophage Differentiation Increases Expression of the Ascorbate Transporter SVCT2
    Qiao, Huan
    FREE RADICAL BIOLOGY AND MEDICINE, 2008, 45 : S36 - S37
  • [3] Modulation of microglia activation by the ascorbic acid transporter SVCT2
    Marino, Amanda L.
    Rex, Tonia S.
    Harrison, Fiona E.
    BRAIN BEHAVIOR AND IMMUNITY, 2024, 120 : 557 - 570
  • [4] Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2
    Harrison, Fiona E.
    May, James M.
    FREE RADICAL BIOLOGY AND MEDICINE, 2009, 46 (06) : 719 - 730
  • [5] VITAMIN C FUNCTION IN THE BRAIN: VITAL ROLE OF THE ASCORBATE TRANSPORTER, SVCT2
    May, James
    FREE RADICAL BIOLOGY AND MEDICINE, 2009, 47 : S7 - S7
  • [6] Oxidized lipoprotein induces the macrophage ascorbate transporter (SVCT2): Protection by intracellular ascorbate against oxidant stress and apoptosis
    Chi, Xiumei
    May, James M.
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2009, 485 (02) : 174 - 182
  • [7] Sodium-ascorbate cotransport controls intracellular ascorbate concentration in primary astrocyte cultures expressing the SVCT2 transporter
    Korcok, J
    Yan, R
    Siushansian, R
    Dixon, SJ
    Wilson, JX
    BRAIN RESEARCH, 2000, 881 (02) : 144 - 151
  • [8] The Sodium Vitamin C co-Transporter-2 (SVCT2): a key molecule for microglia physiology
    Portugal, C. C.
    Socodato, R.
    Canedo, T.
    Silva, C.
    Martins, T.
    Coreixas, V.
    Loiola, E. C.
    Gess, B.
    Roehr, D.
    Santiago, A. R.
    Young, P.
    Paes-de-Carvalho, R.
    Ambrosio, A.
    Relvas, J.
    GLIA, 2015, 63 : E380 - E380
  • [9] Ascorbate and its transporter SVCT2: The dynamic duo's integrated roles in CNS neurobiology and pathophysiology
    Portugal, Camila C.
    FREE RADICAL BIOLOGY AND MEDICINE, 2024, 212 : 448 - 462
  • [10] The contributions of sodium-dependent vitamin C transporters SVCT1 and SVCT2 to tissue concentrations of ascorbate
    Wilson, JX
    MacLean, ME
    Jaworski, E
    McCormick, K
    Kuo, SM
    FASEB JOURNAL, 2004, 18 (04): : A694 - A694