Preparation of polyethyleneimine nanogels via photo-Fenton reaction

被引:17
|
作者
Xu, Dongmei
Hong, Jun
Sheng, Kanglong
Dong, Li
Yao, Side
机构
[1] Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
基金
中国国家自然科学基金;
关键词
photo-fenton reaction; nanogels; self-assembly; UV; polyethyleneimine;
D O I
10.1016/j.radphyschem.2007.02.007
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Photo-Fenton reaction was used to prepare polyethyleneimine nanogels (M-PEls) from PEI pre-polymer as potential non-viral gene delivery vectors. Competition between crosslinking and scission of PEI pre-polymer in assembled cluster made the size of particles homogeneous. Morphologies of the nanoparticles in every step showed the existence of self-assembly in aqueous solution. The results indicated that the crosslinking of PEI pre-polymer was mainly initiated via hydrogen abstraction by hydroxyl radicals generated in the systems. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1606 / 1611
页数:6
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