Development and Dysgenesis of the Cerebral Cortex: Malformations of Cortical Development

被引：46
|
作者：
Raybaud, Charles [1 ]
Widjaja, Elysa [1 ]
机构：
[1] Hosp Sick Children, Div Neuroradiol, Toronto, ON M5G 1X8, Canada
来源：
NEUROIMAGING CLINICS OF NORTH AMERICA | 2011年 / 21卷 / 03期
关键词：
Cortex; development; Focal cortical dysplasia; Microcephaly; Macrocephaly; Lissencephaly; Cobblestone brain; Nodular heterotopia; Schizencephaly; Polymicrogyria; PERINATAL BRAIN-DAMAGE; PERIVENTRICULAR NODULAR HETEROTOPIA; WHITE-MATTER ABNORMALITIES; STURGE-WEBER SYNDROME; NEURONAL MIGRATION; MAGNETIZATION-TRANSFER; BLOOD-FLOW; INTRACTABLE EPILEPSY; FUNCTIONAL MRI; PERISYLVIAN POLYMICROGYRIA;
D O I：
10.1016/j.nic.2011.05.014
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The cerebral cortex develops in several stages from a pseudostratified epithelium at 5 weeks to an essentially complete cortex at 47 weeks. Cortical connectivity starts with thalamocortical connections in the 3rd trimester only and continues until well after birth. Vascularity adapts to proliferation and connectivity. Malformations of cortical development are classified into disorders of specification, proliferation/apoptosis, migration, and organization. However, all processes are intermingled, as for example a dysplastic cell may migrate incompletely and not connect appropriately. However, this classification is convenient for didactic purposes as long as the complex interactions between the different processes are kept in mind.
引用
收藏
页码：483 / +
页数：62
相关论文
共 50 条
  • [1] Cerebral activation in malformations of cortical development
    Richardson, MP
    Koepp, MJ
    Brooks, DJ
    Coull, JT
    Grasby, P
    Fish, DR
    Duncan, JS
    BRAIN, 1998, 121 : 1295 - 1304
  • [2] Malformations of Cerebral Cortex Development: Molecules and Mechanisms
    Juric-Sekhar, Gordana
    Hevner, Robert F.
    ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 14, 2019, 14 : 293 - 318
  • [3] Malformations of cerebral cortical development clinical and imaging features
    Koc, Zafer
    Koc, Filiz
    Kaderoglu, Haydar
    NEUROSURGERY QUARTERLY, 2007, 17 (01) : 23 - 28
  • [4] Complex central cortex in pediatric patients with malformations of cortical development
    Akai, T
    Otsubo, H
    Pang, EW
    Rutka, JT
    Chitoku, S
    Weiss, SK
    Snead, OC
    JOURNAL OF CHILD NEUROLOGY, 2002, 17 (05) : 347 - 352
  • [5] Mutation screening in genes for cortex development in patients with cortical malformations
    Souza, DA
    Torres, FR
    Lopes, CF
    Rodrigues, MCS
    Montenegro, MA
    Llerena, JC
    Piovesana, ASG
    Guerreiro, MM
    Marques-de-Faria, AP
    Cendes, F
    Lopes-Cendes, I
    EPILEPSIA, 2005, 46 : 96 - 96
  • [6] Development of the cerebral cortex: X. Cortical development and experience: II
    Hockfield, S
    Lombroso, PJ
    JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1998, 37 (10): : 1103 - 1105
  • [7] Development of the cerebral cortex: IX. Cortical development and experience: I
    Hockfield, S
    Lombroso, PJ
    JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1998, 37 (09): : 992 - 993
  • [8] MALFORMATIONS OF CORTICAL DEVELOPMENT
    Guerreiro, Marilisa M.
    ARQUIVOS DE NEURO-PSIQUIATRIA, 2009, 67 (2B) : 570 - 574
  • [9] Malformations of cortical development
    Barkovich, AJ
    Raybaud, CA
    NEUROIMAGING CLINICS OF NORTH AMERICA, 2004, 14 (03) : 401 - +
  • [10] Malformations of Cortical Development
    Kanekar, Sangam
    Gent, Michael
    SEMINARS IN ULTRASOUND CT AND MRI, 2011, 32 (03) : 211 - 227
12345