Considerations for multi-centre conditioned pain modulation (CPM) research; an investigation of the inter-rater reliability, level of agreement and confounders for the Achilles tendon and Triceps Surae

被引:5
|
作者
Murphy, Myles [1 ,2 ]
Gibson, William [1 ]
Chivers, Paola [3 ,4 ,5 ]
Docking, Sean [6 ]
Rio, Ebonie [6 ]
机构
[1] Univ Notre Dame Australia, Sch Physiotherapy, 19 Mouat St POB 12251, Fremantle, WA 6959, Australia
[2] St John God Hlth Care, SportsMed Subiaco, Subiaco, WA, Australia
[3] Univ Notre Dame Australia, Inst Hlth Res, Fremantle, WA, Australia
[4] Edith Cowan Univ, Exercise Med Res Inst, Joondalup, WA, Australia
[5] Edith Cowan Univ, Sch Med & Hlth Sci, Joondalup, WA, Australia
[6] La Trobe Univ, La Trobe Sport & Exercise Med Res Ctr, Bundoora, Vic, Australia
基金
澳大利亚国家健康与医学研究理事会;
关键词
Pain; conditioned pain modulation; pressure pain thresholds; pressure pain threshold; exercise rehabilitation; TEMPORAL SUMMATION; SAMPLE-SIZE;
D O I
10.1177/2049463720912208
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: This study aimed to investigate the inter-rater reliability of the conditioned pain modulation (CPM) effect. Methods: The reliability between two examiners assessing the CPM effect via pressure pain thresholds and induced using the cold pressor test of 28 healthy volunteers at the mid-portion Achilles tendon (AT) and Triceps Surae musculotendinous junction was performed. Reliability was calculated using intraclass correlation coefficient (ICC). Confounders were assessed using multivariable generalised estimating equations (GEES). Bias in the level of agreement was assumed if the confidence intervals (Cis) of the mean difference in Bland-Altman plots did not cross the line of equality. Results: The inter-rater reliability of the CPM effect was poor to moderate in the AT (ICC 95% CI =0.00-0.66) and Triceps Surae (ICC 95% CI =0.00-0.69). However, when accounting for confounders within the GEE, there were no differences between testers and Bland-Altman plots reported good agreement between testers. Habitual completion of running-related physical activity was a confounder for both the AT parallel-paradigm (p=0.017) and sequential-paradigm (p=0.029). Testing order was a confounder for the AT (p=0.023) and Triceps Surae (p=0.014) parallel-paradigm. Conclusion: This study suggests the CPM effect may be site specific (i.e. differences between the AT and Triceps Surae exist). In addition, differences in the reliability between examiners are likely due to the influence of confounders and not examiner technique and therefore appropriate analysis should be used in research investigating the CPM effect.
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页码:91 / 101
页数:11
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