Pseudomonas aeruginosa in cystic fibrosis: pathogenesis and new treatments

被引:19
|
作者
Brugha, Rossa E. [4 ]
Davies, Jane C. [1 ,2 ,3 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Paediat Resp Med, London SW3 6NP, England
[2] Univ London Imperial Coll Sci Technol & Med, Dept Gene Therapy, London SW3 6NP, England
[3] Royal Brompton & Harefield NHS Fdn Trust, London SW3 6NP, England
[4] Barts & London Queen Marys Sch Med & Dent, Ctr Paediat, Blizard Inst Cell & Mol Sci, London, England
关键词
AIRWAY PSEUDOMONAS; INFECTIONS; EFFICACY; SURFACE; SAFETY;
D O I
10.12968/hmed.2011.72.11.614
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pseudomonas aeruginosa is the most problematic organism in patients with cystic fibrosis. This article reviews its pathogenic mechanisms, with particular relevance to the pathophysiology of the cystic fibrosis airway, and recent advances in therapeutic approaches.
引用
收藏
页码:614 / 619
页数:6
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