Uterine Sarcoma With a Novel WWOX-NTRK2 Fusion in a Postmenopausal Woman With Li-Fraumeni-Like Syndrome: A Case That Expands the Spectrum of NTRK-Rearranged Uterine Tumors

被引：6

作者：

Moh, Michelle ^{[1
]}

Johnson, Colin M. ^{[2
]}

Geurts, Jennifer ^{[3
]}

Bishop, Erin ^{[4
]}

机构：

[1] Med Coll Wisconsin, Dept Pathol, Milwaukee, WI 53226 USA

[2] Med Coll Wisconsin, Dept Obstet & Gynecol, Milwaukee, WI 53226 USA

[3] Med Coll Wisconsin, Dept Genet Counseling, Milwaukee, WI 53226 USA

[4] Med Coll Wisconsin, Dept Gynecol Oncol, Milwaukee, WI 53226 USA

来源：

AJSP-REVIEWS AND REPORTS | 2021年 / 26卷 / 06期

关键词：

Uterine sarcoma; NTRK2; Li-Fraumeni-like syndrome;

D O I：

10.1097/PCR.0000000000000476

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

NTRK-rearranged tumors are being increasingly recognized and targeted with TRK inhibitor therapies. A novel NTRK2 fusion-positive uterine sarcoma arising in a patient with Li-Fraumeni-like syndrome is described in this article.

引用

页码：304 / 306

页数：3

共 4 条

[1] Case report: STRN3-NTRK3 fusion in uterine sarcoma with spleen metastasis: a new variant in the spectrum of NTRK-rearranged tumors
Colombo, Piergiuseppe
Buonamassa, Giuseppina Adriana
Giulianini, Anita
Hassan, Letizia
Rudini, Noemi
Rizzo, Antonio
Cavallo, Enrico
Carnaghi, Carlo
Goudarzi, Salumeh
Mongiovi, Sebastiano
Pafumi, Sarah
Marletta, Stefano
FRONTIERS IN MEDICINE, 2024, 11
[2] NTRK-rearranged spindle cell sarcoma of the uterine cervix with a novel NUMA1::NTRK1 fusion
Szalai, Luca
Vereczkey, Ildiko
Szemes, Marianna
Rokusz, Andras
Csernak, Erzsebet
Toth, Erika
Melegh, Zsombor
VIRCHOWS ARCHIV, 2024, 484 (03) : 527 - 531
[3] NTRK-rearranged spindle cell sarcoma of the uterine cervix with a novel NUMA1::NTRK1 fusion
Luca Szalai
Ildikó Vereczkey
Marianna Szemes
András Rókusz
Erzsébet Csernák
Erika Tóth
Zsombor Melegh
Virchows Archiv, 2024, 484 : 527 - 531
[4] Uterine Cervical Sarcoma With a Novel RET-SPECC1L Fusion in an Adult A Case Which Expands the Homology Between RET-rearranged and NTRK-rearranged Tumors
Weisman, Paul S.
Altinok, Morgan
Carballo, Erica V.
Kushner, David M.
Kram, Jessica J. F.
Ladanyi, Marc
Chiang, Sarah
Buehler, Darya
Michelson, Elizabeth L.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2020, 44 (04) : 567 - 570

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