Glycopyrrolate/Formoterol Fumarate Fixed-Dose Combination Delivered by Metered Dose Inhaler Improves Lung Function and Symptoms in Patients with COPD: Results from the PINNACLE-4 Study in Asia, Europe, and the USA

被引:0
|
作者
Lipworth, B. [1 ]
Collier, D. J. [2 ]
Gon, Y. [3 ]
Zhong, N. [4 ]
Nishi, K. [5 ]
Chen, R. [4 ]
Arora, S. [6 ]
Maes, A. [7 ]
Siddiqui, S. [8 ]
Reisner, C. [7 ]
Martin, U. J. [8 ]
机构
[1] Univ Dundee, Ninewells Hosp, Scottish Ctr Resp Res, Dundee, Scotland
[2] Queen Mary Univ London, William Harvey Res Inst, Barts & London Sch Med & Dent, London, England
[3] Nihon Univ, Itabashi Hosp, Sch Med, Itabashi Ku, Tokyo, Japan
[4] Guangzhou Med Univ, Affiliated Hosp 1, Natl Clin Res Ctr Resp Dis, Guangzhou Inst Resp Dis,State Key Lab Resp Dis, Guangzhou, Guangdong, Peoples R China
[5] Ishikawa Prefectural Cent Hosp, Kanazawa, Ishikawa, Japan
[6] Aventiv Res Inc, Columbus, OH USA
[7] Pearl Therapeut Inc, Morristown, NJ USA
[8] AstraZeneca, Gaithersburg, MD USA
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A4236
引用
下载
收藏
页数:3
相关论文
共 50 条
  • [1] Effect Of Glycopyrrolate/formoterol Fumarate Fixed-Dose Combination Metered Dose Inhaler (gff Mdi) Delivered By Novel Co-Suspension™ Delivery Technology On Daily Symptoms In Patients With COPD
    Martinez, F. J.
    Fabbri, L. M.
    Ferguson, G. T.
    Orevillo, C.
    Darken, P.
    Martin, U. J.
    Reisner, C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
  • [2] Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Improves Lung Function versus Monotherapies in GOLD Category A Patients with COPD: Pooled Data from the Phase III PINNACLE Studies
    Martinez, Fernando J.
    Rabe, Klaus F.
    Lipworth, Brian J.
    Arora, Samir
    Jenkins, Martin
    Martin, Ubaldo J.
    Reisner, Colin
    INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2020, 15 : 99 - 106
  • [3] Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler (GFF MDI) Improves Lung Function in GOLD Category A Patients with COPD: Pooled Data from the Phase III PINNACLE Studies
    Martinez, F. J.
    Rabe, K. F.
    Lipworth, B. J.
    Arora, S.
    Jenkins, M.
    Maes, A.
    Martin, U. J.
    Reisner, C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
  • [4] Cardiovascular safety profile of a fixed-dose combination of glycopyrrolate and formoterol fumarate delivered via metered dose inhaler using co-suspension delivery technology
    Ferguson, Gary T.
    Reisner, Colin
    Pearle, James
    DePetrillo, Paolo
    Maes, Andrea
    Martin, Ubaldo J.
    PULMONARY PHARMACOLOGY & THERAPEUTICS, 2018, 49 : 67 - 74
  • [5] Benefits of Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler (GFF MDI) in Symptomatic Patients with COPD: A Post-Hoc Analysis from a Phase III, Randomized, Placebo-Controlled Study (PINNACLE-4)
    Lipworth, B. J.
    Collier, D. J.
    Feldman, G. J.
    Arora, S.
    Jenkins, M.
    Reisner, C.
    Martin, U. J.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
  • [6] Improvements in lung function with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler versus dual therapies in patients with COPD: a sub-study of the ETHOS trial
    Rabe, Klaus F.
    Martinez, Fernando J.
    Singh, Dave
    Trivedi, Roopa
    Jenkins, Martin
    Darken, Patrick
    Aurivillius, Magnus
    Dorinsky, Paul
    THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE, 2021, 15
  • [7] Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA
    Lipworth, Brian J.
    Collier, David J.
    Gon, Yasuhiro
    Zhong, Nanshan
    Nishi, Koichi
    Chen, Rongchang
    Arora, Samir
    Maes, Andrea
    Siddiqui, Shahid
    Reisner, Colin
    Martin, Ubaldo J.
    INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2018, 13 : 2969 - 2984
  • [8] A multicenter, randomized, double-blind dose-ranging study of glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler compared to the monocomponents and open-label tiotropium dry powder inhaler in patients with moderate-to-severe COPD
    Tashkin, Donald P.
    Martinez, Fernando J.
    Rodriguez-Roisin, Roberto
    Fogarty, Charles
    Gotfried, Mark
    Denenberg, Michael
    Gottschlich, Gregory
    Donohue, James F.
    Orevillo, Chad
    Darken, Patrick
    St Rose, Earl
    Strom, Shannon
    Fischer, Tracy
    Golden, Michael
    Reisner, Colin
    RESPIRATORY MEDICINE, 2016, 120 : 16 - 24
  • [9] Cardiovascular Safety Profile Of A Novel Lama/laba Co-Suspension Technology Fixed-Dose Combination Of Glycopyrrolate/formoterol Delivered By Metered Dose Inhaler In Patients With COPD: 24-Hour Holter Monitoring Study
    Martinez, F. J.
    Fabbri, L. M.
    Rennard, S. I.
    Sethi, S.
    Gottschlich, G.
    Arora, S.
    Darken, P.
    Orevillo, C.
    Siddiqui, S.
    Reisner, C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
  • [10] Pharmacokinetic And Safety Profile Of A Novel Co-Suspension Technology Fixed-Dose Combination Of Budesonide/glycopyrrolate/formoterol Delivered By Metered Dose Inhaler In Healthy Adult Subjects
    Orevillo, C.
    Miller, J.
    DePetrillo, P.
    Siddiqui, S.
    Ballal, S.
    Reisner, C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193