Preparation of 4-alkyl-2-[N-(tert-butoxycarbonyl)amino]-pyridines by alkylation, nucleophilic addition, and acylation of 2-[N-(tert-butoxycarbonyl)amino]-4-picoline

被引：7
|
作者：
Ihle, NC
Krause, AE
机构：
[1] Medicinal Chemistry Department, Merck and Co., West Point
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 14期
关键词：
D O I：
10.1021/jo960184t
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[No abstract available]
引用
下载
收藏
页码：4810 / 4811
页数：2
相关论文
共 50 条
  • [1] N-(tert-butoxycarbonyl)-2-phenylglycine
    GonzalezCameno, AM
    Badia, D
    Dominguez, E
    Arriortua, MI
    Urtiaga, MK
    Solans, X
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1996, 52 : 3169 - 3171
  • [2] Synthesis of unusual amino acids:: N-(tert-butoxycarbonyl)-L-vinyl glycine and N-(tert-butoxycarbonyl)-L-homophenylalanine
    Chandrasekhar, S
    Raza, A
    Takhi, M
    TETRAHEDRON-ASYMMETRY, 2002, 13 (04) : 423 - 428
  • [3] STRUCTURE OF N-(TERT-BUTOXYCARBONYL)GLYCINE
    SEMERTZIDIS, M
    MATSOUKAS, J
    NASTOPOULOS, V
    HONDRELIS, J
    VOLIOTIS, S
    LEBAN, I
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 1989, 45 : 1474 - 1475
  • [4] PREPARATION OF TETRAHYDROISOQUINOLINES FROM N-(TERT-BUTOXYCARBONYL)-2-METHYLBENZYLAMINES
    CLARK, RD
    JAHANGIR
    HETEROCYCLES, 1991, 32 (09) : 1699 - 1703
  • [5] Uncatalyzed addition of N-(tert-butoxycarbonyl)-2-tert-butyidimethylsilyloxypyrrole to activated quinones
    Brimble, MA
    Halim, R
    Petersson, M
    TETRAHEDRON LETTERS, 2002, 43 (27) : 4777 - 4780
  • [6] ORTHO FUNCTIONALIZATION OF N-(TERT-BUTOXYCARBONYL)ANILINE
    MUCHOWSKI, JM
    VENUTI, MC
    JOURNAL OF ORGANIC CHEMISTRY, 1980, 45 (23): : 4798 - 4801
  • [7] X-RAY AND IR STUDIES OF N-(TERT-BUTOXYCARBONYL)-L-ALANINE - COMPARISON WITH N-(TERT-BUTOXYCARBONYL)GLYCINE
    VANMEERVELT, L
    DEWAEL, K
    ZEEGERSHUYSKENS, T
    JOURNAL OF MOLECULAR STRUCTURE, 1995, 356 (03) : 183 - 190
  • [8] Benzyl-5-[N-(tert-butoxycarbonyl)amino]-4-oxo-6-phenylhexanoate
    Våbeno, J
    Ingebrigtsen, T
    Lejon, T
    Luthman, K
    Hansen, LK
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O1331 - O1332
  • [9] PREPARATION OF INDOLES AND OXINDOLES FROM N-(TERT-BUTOXYCARBONYL)-2-ALKYLANILINES
    CLARK, RD
    MUCHOWSKI, JM
    FISHER, LE
    FLIPPIN, LA
    REPKE, DB
    SOUCHET, M
    SYNTHESIS-STUTTGART, 1991, (10): : 871 - 878
  • [10] Oxidation of methyl heteroaryls with molecular oxygen:: A facile synthesis of 2-[N-(tert-butoxycarbonyl)amino]-4-pyridinecarbaldehyde
    Berlin, Michael
    Aslanian, Robert
    de Lera Ruiz, Manuel
    McCormick, Kevin D.
    SYNTHESIS-STUTTGART, 2007, 16 (16): : 2529 - 2533
12345