Distribution and Risk Factors of Multidrug-Resistant Bacteria Infection in Orthopedic Patients

Objective. To study the distribution and risk factors of multidrug-resistant bacteria (MDROS) infection in orthopedic patients and to provide reference for clinical prevention and control measures. Methods. The data of 239 inpatients with orthopedic trauma from June 2019 to December 2020 were selected as the research objects, and the distribution characteristics of MDROS infection were analyzed through the real-time monitoring system of nosocomial infection. Logistic regression analysis was used to screen out the risk factors causing MDROS infection, and the preventive measures were put forward. Results. 178 strains of pathogens were isolated from 239 patients, including 53 strains of MDROS, and the detection rate was 29.78%. The main pathogenic bacteria were ESBLs, MRSA, CRAB, CRE, and MDR/PDRPA. The main infection sites of MDROS in orthopedic patients were the respiratory tract and wound. No CRE1 was detected, and 64.39%, 17.42%, and 14.39% of ESBL-producing bacteria, MRSA, and MDR/PDRPA, respectively, were detected. Logistic multivariate analysis showed that the length of hospital stay, antibiotic use time, open injury, and serum albumin level were independent risk factors of MDROS infection in orthopedic trauma patients. Conclusion. To prevent MDROS infection in orthopedic patients, we should start from many aspects, focusing on reducing unnecessary hospitalization days, rationally preventing the use of antibacterial drugs, effectively treating basic diseases, etc., timely and effective thorough debridement, strengthening functional training, reducing bed rest, and strengthening targeted monitoring of related infections which are the keys to reduce MDROS infection in orthopedic patients.