Pitfalls of Insulin-like Growth Factor-I and Growth Hormone Assays

被引：37

作者：

Junnila, Riia K. ^{[1
]}

Strasburger, Christian J. ^{[2
]}

Bidlingmaier, Martin ^{[1
]}

机构：

[1] Univ Munich, Med Klin & Poliklin 4, Endocrine Res Unit, D-80336 Munich, Germany

[2] Charite, Dept Endocrinol & Metab Dis, D-10117 Berlin, Germany

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2015年 / 44卷 / 01期

关键词：

Growth hormone; Insulin-like growth factor I; Immunoassay; Binding protein; Standard preparation; Antibody; Provocative testing; IGF-I; CUTOFF LIMITS; GH SECRETION; REFERENCE INTERVALS; STIMULATION TESTS; MASS-SPECTROMETRY; SENSITIVE ASSAY; HEALTHY-ADULTS; HUMAN-SERUM; AGE;

D O I：

10.1016/j.ecl.2014.10.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Accurate measurement of growth hormone (GH) and insulin-like growth factor-I (IGF-I) are the key to correct diagnosis of acromegaly and GH deficiency. Unfortunately, there is much variation involved when these hormones are measured at different sites and using different assay methods. There is an ongoing global effort to standardize the measurement process to obtain more comparable results in the future. This review discusses common pitfalls in the measurement of GH and IGF-I and guides laboratories in their analyses of these hormones.

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页码：27 / +

页数：9

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