Simple methods to synthesize 2-pyridones: reactions of 2-aroyl-3,3-bis(alkylsulfanyl)acrylaldehydes and cyanoacetamide

被引：14
|
作者：
Mathews, Annie [1 ]
Anabha, E. R. [2 ]
Sasikala, K. A. [2 ]
Lathesh, K. C. [2 ]
Krishnaraj, K. U. [2 ]
Sreedevi, K. N. [2 ]
Prasanth, M. [2 ]
Devaky, K. S. [2 ]
Asokan, C. V. [2 ]
机构：
[1] Baselius Coll, Postgrad Dept Chem, Kottayam 686001, Kerala, India
[2] Mahatma Gandhi Univ, Sch Chem Sci, Kottayam 686560, Kerala, India
来源：
TETRAHEDRON | 2008年 / 64卷 / 08期
关键词：
heterocycles; thermal cyclization; acrylaldehydes; dithioacetals; 2-pyridones;
D O I：
10.1016/j.tet.2007.12.012
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-Aroyl-6-(methylsulfanyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitriles and 5-aroyl-4-(methylsulfanyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitriles are synthesized effectively by the reaction of 2-aroyl-3,3-bis(alkylsulfanyl)acrylaldehydes and cyanoacetamide under two different conditions. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1671 / 1675
页数：5
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