2-[(3,5-Diamino-1H-pyrazol-4-yl)methylidene]-1,2-dihydro-3H-indol-3-ones: synthesis and properties

被引：2

作者：

Masterova, N. S. ^{[1
]}

Ryabova, S. Yu. ^{[1
]}

Alekseeva, L. M. ^{[1
]}

Shashkov, A. S. ^{[2
]}

Chernyshev, V. V. ^{[3
]}

Granik, V. G. ^{[1
]}

机构：

[1] State Res Ctr Antibiot, Moscow 117003, Russia

[2] Russian Acad Sci, ND Zelinskii Organ Chem Inst, Moscow 119991, Russia

[3] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119899, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2009年 / 58卷 / 09期

关键词：

3-acetoxy-2-(2,2-dicyanovinyl)indole; hydrazines; 2-[(3,5-diamino-1H-pyrazol-4-yl)methylidene]indolin-3-ones; acetylation; X-ray diffraction analysis; DMF and DMAA dimethyl acetals; cyclization; pyrazolo[4 ',3 ':5,6]pyrido[3,2-b]indole; POWDER DIFFRACTION; DERIVATIVES; RELIABILITY; PYRIMIDINE; CRITERION; NITRILES; PROGRAM;

D O I：

10.1007/s11172-009-0269-y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of 3-acetoxy-2-(2,2-dicyanovinyl)indole with hydrazine hydrate and methyl-and phenylhydrazines afforded new indolin-3-one derivatives, namely, 2-[( 3,5-diaminopyrazol-4-yl)methylidene]indolin-3-ones. Reactions of the compounds obtained with acetic anhydride and DMF and DMAA dimethyl acetals were studied. Cyclization of 2-[(3,5-diamino-1H-pyrazol-4-yl)methylidene]-1,2-dihydro-3H-indolinone gave 3-amino-1,5-dihydropyrazolo-[4',3' : 5,6]pyrido[3,2-b]indole, a representative of a novel heterocyclic system.

引用

页码：1973 / 1980

页数：8

共 50 条

[1] 2-[(3,5-Diamino-1H-pyrazol-4-yl)methylidene]-1,2-dihydro-3H-indol-3-ones: Synthesis and properties
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S. Yu. Ryabova
L. M. Alekseeva
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V. V. Chernyshev
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Russian Chemical Bulletin, 2009, 58 : 1973 - 1980
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