The behaviour of some nucleophiles towards 2-[α-benzoylamino-β-2-thienylvinyl]benzoxazin-4(3H)-one

被引：0
|
作者：
Guirguis, DB [1 ]
机构：
[1] Ain Shams Univ, Fac Sci, Dept Chem, Cairo, Egypt
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2000年 / 39卷 / 04期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
2-[alpha -Benzoylamino-beta -2-thienylvinyl]benzoxazin-4(3H)-one 3 undergoes ring opening reaction on treatment with primary and secondary amines affording the compounds 4a-c, 5 and 6a,b. Treatment of the title compound with formamide and hydrazine hydrate at elevated temperature gives rise to quinazolinone derivatives 7 and 8. Interestingly, the vicinal aminobenzyl alcohols on treatment with 3 undergo ring opening reaction giving rise to compounds 12a-c and the newly unexpected benzoxaiine 13a,b with molar ratios 1:1 and 1:2, respectively.
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页码：264 / 269
页数：6
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