Fluorescence Imaging of Azobenzene Photoswitching In Vivo

被引:127
|
作者
Beharry, Andrew A. [1 ]
Wong, Loksum [2 ]
Tropepe, Vince [2 ]
Woolley, G. Andrew [1 ]
机构
[1] Univ Toronto, Dept Chem, 80 St George St, Toronto, ON M5S 3H6, Canada
[2] Univ Toronto, Dept Cell & Syst Biol, Toronto, ON M5S 3G5, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
azobenzene; fluorescence; peptides; photo-control; photoisomerization; PHOTOCONTROL;
D O I
10.1002/anie.201006506
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Switching zebrafish: A fluorescent reporter peptide permits imaging of azobenzene photoisomerization in vivo (see picture), which indicates that azobenzene-based photochemical switches may be generally useful for spatiotemporal control in living systems. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:1325 / 1327
页数:3
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