COmparisoN of TastES of Available NutriTional integrated or non-integrated formulas for infants older than 1 year of age with cow's milk allergy: A multicenter, prospective, single blind, cross-sectional observational clinical study (CONTEST Study)

被引：3

作者：

Altintas, Derya Ufuk ^{[1
]}

Turktas, Ipek ^{[2
]}

Arga, Mustafa ^{[3
]}

Cokugras, Haluk Cezmi ^{[4
]}

Civelek, Ersoy ^{[5
]}

Keskin, Ozlem ^{[6
]}

Buyuktiryaki, Betul ^{[7
]}

Ertem, Deniz ^{[8
]}

Aydogan, Metin ^{[9
]}

Ecevit, Cigdem Omur ^{[10
]}

Ozturk, Yesim ^{[11
]}

Tamay, Zeynep ^{[12
]}

Yucel, Esra ^{[12
]}

Caltepe, Gonul ^{[13
]}

Beser, Omer Faruk ^{[14
]}

Guler, Nermin ^{[12
]}

机构：

[1] Cukurova Univ, Sch Med, Dept Pediat, Pediat Allergy & Immunol Div, Adana, Turkey

[2] Gazi Univ, Sch Med, Dept Pediat, Pediat Allergy & Immunol Div, Ankara, Turkey

[3] Medeniyet Univ, Sch Med, Dept Pediat, Pediat Allergy & Immunol Div, Istanbul, Turkey

[4] Cerrahpasa Sch Med, Dept Pediat, Pediat Allergy & Immunol Div, Istanbul, Turkey

[5] Ankara Childrens Haematol Oncol Training & Res Ho, Pediat Allergy & Immunol Div, Ankara, Turkey

[6] Gaziantep Univ, Sch Med, Dept Pediat, Pediat Allergy & Immunol Div, Gaziantep, Turkey

[7] Koc Univ, Sch Med, Dept Pediat, Pediat Allergy Div, Istanbul, Turkey

[8] Marmara Univ, Sch Med, Dept Pediat, Pediat Gastroenterol Div, Istanbul, Turkey

[9] Kocaeli Univ, Sch Med, Dept Pediat, Pediat Allergy & Immunol Div, Kocaeli, Turkey

[10] Hlth Sci Univ, Dr Behcet Uz Child Dis & Pediat Surg Training & R, Pediat Gastroenterol Div, Izmir, Turkey

[11] 9 Eylul Univ, Dept Pediat, Pediat Gastroenterol Div, Sch Med, Izmir, Turkey

[12] Istanbul Univ, Sch Med, Dept Pediat, Pediat Allergy & Immunol Div, Istanbul, Turkey

[13] 19 Mayis Univ, Sch Med, Dept Pediat, Pediat Gastroenterol Div, Samsun, Turkey

[14] Okmeydani Training & Res Hosp, Clin Pediat, Pediat Gastroenterol Div, Istanbul, Turkey

来源：

ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2022年 / 50卷 / 04期

关键词：

Cow's milk protein allergy; taste perception; protein hydrolysates; infant formula; compliance; FLAVOR EXPERIENCES; PREFERENCES; HYDROLYSATE; CHILDHOOD; PEPTIDES;

D O I：

10.15586/aei.v50i4.520

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Palatability of the infant formulas lacking cow milk protein formulas is reported by parents to be an important drawback. The purpose of this study is to examine decisions made by mothers of infants having cow milk protein allergy, and physicians concerning the palatability of unflavored extensively hydrolyzed formulas and amino acid-based formulas. We conducted a multi-center, randomized, single-blinded, observational taste study involving 149 pediatricians from gastroenterology and allergy subspecialties at 14 tertiary healthcare units from different regions of Turkey and involving 94 mothers of infants with cow milk protein allergy. Blinding was performed for seven formulas available in the market, which were the most commonly prescribed for feeding: four AAFs (Neocate-Numil((R)), Aptamil Pregomin AS-Numil((R)), Alfamino-Nestle((R)), Comidagen-Mamma((R))), one AAF specifically designed to address the growing nutritional and lifestyle needs of children >1 year (Neocate Junior-Numil((R))), 2 eHFs (Bebelac Pepti Junior-Numil((R)), Similac Alimentum-Abott((R))). Considering all three formula characteristics, Neocate junior-Numil((R)) ranked as the number 1 product among seven products by mothers (63.8%) and physicians (69.8%). The ratings of mothers were significantly higher than the physicians (8.1 points and 6.1 points, respectively; p < 0.001). No difference was found in terms of taste, smell, and appearance for Neocate junior-Numil((R)) between the mothers' and physicians' ratings. Since caregivers have responsibility for careful selection of replacement products for infants with cow milk protein allergy, it is noteworthy that increased awareness and confidence in the palatability characteristics of these products should motivate mothers and physicians to comply with replacement treatment in the long term. (c) 2022 Codon Publications. Published by Codon Publications.

引用

页码：97 / 104

页数：8