Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non- invasive strategy building from a cross sectional study in a low resource setting

被引：3

作者：

Anand, Aishwarya ^{[1
]}

Kumar, Rupesh ^{[2
]}

Gupta, Ankur ^{[3
,7
]}

Vijayvergiya, Rajesh ^{[3
]}

Mehrotra, Saurabh ^{[3
]}

Lad, Deepesh ^{[4
]}

Barwad, Parag ^{[3
]}

Sharma, Swati ^{[5
]}

Patil, Amol N. ^{[1
,6
]}

机构：

[1] Postgrad Inst Med Educ & Res PGIMER, Dept Pharmacol, Chandigarh, India

[2] Postgrad Inst Med Educ & Res PGIMER, Dept Cardiothorac & Vasc Surg, Chandigarh, India

[3] Postgrad Inst Med Educ & Res PGIMER, Dept Cardiol, Chandigarh, India

[4] Postgrad Inst Med Educ & Res PGIMER, Dept Internal Med, Chandigarh, India

[5] Postgrad Inst Med Educ & Res PGIMER, Dept Expt Med & Biotechnol, Chandigarh, India

[6] PGIMER, Dept Pharmacol, Chandigarh 160012, India

[7] PGIMER, Dept Cardiol, Chandigarh, India

来源：

INDIAN HEART JOURNAL | 2022年 / 74卷 / 03期

关键词：

Warfarin nomogram; Percent time in therapeutic range; INR; ATRIAL-FIBRILLATION;

D O I：

10.1016/j.ihj.2022.03.008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A cross-sectional study was conducted to predict time in therapeutic range (TTR) using clinical history, examination, and socioeconomic data. Study included warfarin-receiving patients from outpatient-clinic. In 203 patients studied, mean warfarin start-dose was 2.55 mg/day and maintenance-dose/week was 30.79 mg. Body mass index (BMI) (p = 0.03), warfarin maintenance dose/day (p = 0.02), and comorbidity presence (p = 0.04) were significantly associated with TTR. Occupation (p = 0.53), income (p = 0.83), education (p = 0.55), and socioeconomic score (p = 0.73) showed non-significant association with TTR. A TTR predicting nomogram was built from clinical history and examination findings. (c) 2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

引用

页码：245 / 248

页数：4