PREPARATION AND APPLICATION OF CHITOSAN NANOPARTICLES AND NANOFIBERS

被引:135
|
作者
Zhao, Li-Ming [1 ]
Shi, Lu-E [2 ]
Zhang, Zhi-Liang [2 ]
Chen, Jian-Min [2 ]
Shi, Dong-Dong [2 ]
Yang, Jie [2 ]
Tang, Zhen-Xing [1 ]
机构
[1] E China Univ Sci & Technol, Coll Biotechnol, Dept Food Sci & Technol, Shanghai 200037, Peoples R China
[2] Hangzhou Normal Univ, Coll Life & Environm Sci, Hangzhou 310036, Zhejiang, Peoples R China
关键词
Chitosan; Encapsulation; Bioactive substances; Immobilization; HYDROPHOBICALLY-MODIFIED CHITOSAN; LINKED ENZYME CRYSTALS; ACID-MODIFIED CHITOSAN; NANO-PARTICLES; VITAMIN-C; AQUEOUS-SOLUTION; ALGINATE BEADS; CROSS-LINKING; STABILITY; IMMOBILIZATION;
D O I
10.1590/S0104-66322011000300001
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
Encapsulation and immobilization technology is important for the food processing and bioengineering industries. Chitosan is a natural polysaccharide prepared by the N-deacetylation of chitin. It has been widely used in food and bioengineering industries, including the encapsulation of active food ingredients, in enzyme immobilization, and as a carrier for controlled drug delivery, due to its significant biological and chemical properties such as biodegradability, biocompatibility, bioactivity, and polycationicity. In this work, chitosan nanoparticles and nanofibers used to encapsulate bioactive substances and immobilize enzymes were reviewed. Preparation of chitosan nanoparticles and nanofibers, including the work achieved in our group on chitosan nanoparticles for enzyme immobilization, were also introduced. Some problems encountered with nano-structured chitosan carriers for bioactive substance encapsulation and enzyme immobilization were discussed, together with the future prospects of such systems.
引用
收藏
页码:353 / 362
页数:10
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