Severe expression of corpus gastritis is characteristic in gastric cancer patients infected with Helicobacter pylori

被引:85
|
作者
Miehlke, S
Hackelsberger, A
Meining, A
Hatz, R
Lehn, N
Malfertheiner, P
Stolte, M
Bayerdörffer, E
机构
[1] Tech Univ Hosp, Dept Med 1, D-01307 Dresden, Germany
[2] Univ Magdeburg, Dept Gastroenterol, D-39106 Magdeburg, Germany
[3] Tech Univ Hosp, Dept Med 2, Munich, Germany
[4] Univ Munich, Klinikum Grosshadern, Dept Surg, D-80539 Munich, Germany
[5] Univ Regensburg, Inst Clin Microbiol, D-8400 Regensburg, Germany
[6] Klinikum Bayreuth, Inst Pathol, Bayreuth, Germany
关键词
Helicobacter pylori; gastric carcinoma; grade of gastritis; activity of gastritis; regenerative epithelium; intestinal metaplasia; focal atrophy; lymphoid follicles;
D O I
10.1038/bjc.1998.475
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In 50 Helicobacter pylori-infected gastric carcinoma patients the corpus gastritis was significantly higher than in matched H. pylori-positive control subjects (P < 0.01). Atrophy and intestinal metaplasia (IM) occurred significantly more often in the antrum of carcinoma patients (P < 0.01). The odds ratio for gastric carcinoma was 8.85 for high-grade corpus gastritis and 8.04 when atrophy in the antrum was present.
引用
收藏
页码:263 / 266
页数:4
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