Boron clusters in medicinal chemistry: perspectives and problems

被引：55
|
作者：
Gabel, Detlef [1 ]
机构：
[1] Jacobs Univ Bremen, Life Sci & Hlth, D-28759 Bremen, Germany
来源：
PURE AND APPLIED CHEMISTRY | 2015年 / 87卷 / 02期
关键词：
boranes; drug development; enzyme inhibitors; IMEBORON XV; medicinal chemistry; pharmacology; CARBABORANE DERIVATIVES; LIPID-MEMBRANES; HIV PROTEASE; INHIBITORS; CARBORANE; DODECABORATE; INDOMETHACIN; LIPOSOMES; DOCKING; ANIONS;
D O I：
10.1515/pac-2014-1007
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Boron clusters have been employed successfully as constituents in bioactive substances. In this review, the perspectives of boron clusters for drug design and problems to be solved for a broader application are discussed, and a list of actions is given for overcoming the problems.
引用
收藏
页码：173 / 179
页数：7
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