The polymorphic deleted-form of the human α2B-adrenergic receptor and its wild-type counterpart display post-receptor signaling pathway differences in LLC-PK1 cells

被引：1

作者：

Mastrogianni, Orthodoxia ^{[1
]}

Crassous, Pierre-Antoine ^{[2
]}

Karkoulias, Georgios ^{[1
]}

Lykouras, Dimosthenis ^{[1
]}

Schaak, Stephane ^{[2
]}

Patsouras, Nicholas ^{[1
]}

Panayiotakopoulos, George ^{[1
]}

Sivolapenko, Gregory ^{[3
]}

Paris, Herve ^{[2
]}

Manolis, Antonis S. ^{[4
]}

Flordellis, Christodoulos ^{[1
]}

机构：

[1] Univ Patras, Sch Med, Dept Pharmacol, Rion 26504, Greece

[2] CHU Rangueil, Inst Louis Bugnard, INSERM Unit 388, IFR31, F-31400 Toulouse, France

[3] Univ Patras, Dept Pharm, Pharmacokinet Lab, Patras, Greece

[4] Univ Athens, Sch Med, Dept Cardiol 3, Athens, Greece

来源：

Hellenic Journal of Cardiology | 2016年 / 57卷 / 04期

关键词：

alpha(2B)-adrenergic receptor; beta-arrestin; MAPK; Akt; NF-kappa B; ARACHIDONIC-ACID METABOLISM; RISK-FACTOR; KAPPA-B; ACTIVATION; TRANSACTIVATION; MAPK; GENE;

D O I：

10.1016/j.hjc.2016.05.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：292 / 295

页数：4

共 3 条

[1] Comparative study of the signaling pathways of the wild-type and deletedform of human α2B-adrenergic receptor, from the membrane to the nucleus
Mastrogianni, O.
Crassous, P. A.
Karkoulias, G.
Schaak, S.
Paris, H.
Flordellis, C.
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2007, 21 : 27 - 27
[2] Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells
Kristy Nguyen
Theodoros Kassimatis
Anastasios Lymperopoulos
Cell Communication and Signaling, 9
[3] Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells
Nguyen, Kristy
Kassimatis, Theodoros
Lymperopoulos, Anastasios
CELL COMMUNICATION AND SIGNALING, 2011, 9

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