Selection and Functionalization of Germanium Nanowires for Bio- Sensing

被引：6

作者：

Laumier, Siriny ^{[1
]}

Farrow, Thomas ^{[1
]}

van Zalinge, Harm ^{[1
]}

Seravalli, Luca ^{[2
]}

Bosi, Matteo ^{[2
]}

Sandall, Ian ^{[1
]}

机构：

[1] Univ Liverpool, Dept Elect Engn & Elect, Liverpool L69 3GJ, England

[2] Inst Mat Elect & Magnetism, I-43124 Parma, Italy

来源：

ACS OMEGA | 2022年

基金：

英国工程与自然科学研究理事会;

关键词：

SENSORS; APTAMERS;

D O I：

10.1021/acsomega.2c04775

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper, we investigate the use of dielectrophoresis to align germanium nanowire arrays to realize nanowire-based diodes and their subsequent use for bio-sensing. After establishing that dielectrophoresis is a controllable and repeatable fabrication method to create devices from germanium nanowires, we use the optimum process conditions to form a series of diodes. These are subsequently functionalized with an aptamer, which is able to bind specifically to the spike protein of SARS-Cov2 and investigated as a potential sensor. We observe a linear increase in the source to drain current as the concentration of spike protein is increased from 100 fM/L to 1 nM/L.

引用

页码：35288 / 35296

页数：9

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