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Effect of estradiol-17β on calcitonin receptor bindings in the hen neurohypophysis
被引:0
|作者:
Nakayama, H.
[1
]
Takahashi, T.
[2
]
Nakagawa-Mizuyachi, K.
[1
]
Kawashima, M.
[1
]
机构:
[1] Gifu Univ, United Grad Sch Agr Sci, Gifu 5011193, Japan
[2] Gifu Univ, Grad Sch Appl Biol Sci, Gifu 5011193, Japan
关键词:
estradiol-17;
beta;
hen neurohypophysis;
calcitonin receptor;
binding affinity;
binding capacity;
ARGININE VASOTOCIN;
LUTEINIZING-HORMONE;
OVULATORY CYCLE;
NONLAYING HENS;
DOMESTIC-FOWL;
PLASMA-LEVELS;
OVIPOSITION;
PROGESTERONE;
RELEASE;
MESOTOCIN;
D O I:
10.3382/ps.2010-00965
中图分类号:
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号:
0905 ;
摘要:
The present study was performed to elucidate whether estradiol-17 beta (E-2) would affect calcitonin (CT) receptor binding in the hen neurohypophysis. The equilibrium dissociation constant (K-d) and the maximum binding capacity (B-max) of the CT receptor in the plasma membrane fraction of the hen neurohypophysis were examined by Scatchard analysis of specific binding of I-125-labeled chicken CT. A single i.m. injection of E-2 into nonlaying hens caused a decrease in K-d and B-max values of the CT receptor. The K-d and B-max values of the CT receptor were smaller in laying hens than in nonlaying hens. The present study suggests that E-2 may increase the action of CT on the neurohypophysis in hens.
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页码:191 / 194
页数:4
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