Proteomic analysis of peritoneal fluid in women with endometriosis

被引：47
|
作者：
Ferrero, Simone
Gillott, David J.
Remorgida, Valentino
Anserini, Paola
Leung, Kit-Yi
Ragni, Nicola
Grudzinskas, Jurgis G.
机构：
[1] Queen Mary Univ London, St Bartholomews Sch Med & Dent, Reprod Physiol Lab, London, England
[2] Univ Genoa, St Marino Hosp, Dept Obstet & Gynaecol, I-16126 Genoa, Italy
[3] Queen Mary Univ London, William Harvey Res Inst, London, England
来源：
JOURNAL OF PROTEOME RESEARCH | 2007年 / 6卷 / 09期
关键词：
endometriosis; peritoneal fluid; tandem mass spectrometry; proteomics; two-dimensional gel; electrophoresis;
D O I：
10.1021/pr060680q
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
This study aims to evaluate differences in the expression of proteins present in the peritoneal fluid (PF) of women with and without endometriosis. PF samples were subjected to two-dimensional gel electrophoresis; protein spots of interest were identified by liquid chromatography tandem mass spectrometry. Several molecules had aberrant expression in PF of women with endometriosis; they may be useful for a better understanding of the pathogenesis of this disease.
引用
收藏
页码：3402 / 3411
页数：10
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