Supercritical carbon dioxide extraction of Usnea longissima (L.) Ach.: Optimization by Box-Behnken design (BBD)

被引：2
|
作者：
Atila Dincer, Ceren [1 ]
Gokalp, Ceren [1 ]
Getiren, Bengu [1 ]
Yildiz, Atila [2 ]
Yildiz, Nuray [1 ]
机构：
[1] Ankara Univ, Fac Engn, Dept Chem Engn, Ankara, Turkey
[2] Ankara Univ, Dept Biol, Ankara, Turkey
来源：
TURKISH JOURNAL OF CHEMISTRY | 2021年 / 45卷 / 04期
关键词：
Usnea longissima (L.) Ach; usnic acid (UA); supercritical extraction; response surface methodology (RSM); FLUID EXTRACTION; USNIC ACID; CO2; EXTRACTION; OPERATING-CONDITIONS; ANTIOXIDANT; LICHEN; SFE;
D O I：
10.3906/kim-2102-66
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Usnic acid (UA) was extracted from Usnea longissima (L.) Ach. in supercritical carbon dioxide (SC-CO2) medium. The selected process parameters were extraction temperature (35-45 degrees C), amount of co-solvent (0%-5%) and extraction time (5-9 h). These parameters were applied to Box-Behnken design (BBD) belonging to response surface methodology (RSM) to determine optimum process parameters for the highest amount of UA in the extract. g UA/100g lichen, extraction yield % and UA content values were calculated in the range of 0.045-0.317, 2.77-5.4 and 71%-82% in different experimental conditions, respectively. The optimum conditions were predicted as 42 degrees C, 4.3% (ethanol) and 7.48 h. It was determined that the predicted and experimental values of g UA/100g lichen were compatible, and the suggested model was valid.
引用
收藏
页码：1248 / 1256
页数：9
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