Using Protein Interaction Networks to Understand Complex Diseases

被引:7
|
作者
Koyutuerk, Mehmet [1 ]
机构
[1] Case Western Reserve Univ, Cleveland, OH 44106 USA
基金
美国国家科学基金会;
关键词
Biotechnology; Proteins; Gene expression; Bioinformatics; Genomics; Biological system modeling; Biological cells; Biomedical informatics; Information theory; information theory; computational biology; genetics; bioinformatics; databases; mining methods and algorithms; graph algorithms; CANCER; PATHWAYS; OPINION;
D O I
10.1109/MC.2012.40
中图分类号
TP3 [计算技术、计算机技术];
学科分类号
0812 ;
摘要
Recent developments in biotechnology have enabled interrogation of the cell at various levels, leading to many types of "omic" data that provide valuable information on multiple genetic and environmental factors and their interactions.
引用
收藏
页码:31 / 38
页数:8
相关论文
共 50 条
  • [1] Prioritisation of associations between protein domains and complex diseases using domain-domain interaction networks
    Wang, W.
    Zhang, W.
    Jiang, R.
    Luan, Y.
    [J]. IET SYSTEMS BIOLOGY, 2010, 4 (03) : 212 - 222
  • [2] Identification of target genes in cancer diseases using protein–protein interaction networks
    Arumugam Amala
    Isaac Arnold Emerson
    [J]. Network Modeling Analysis in Health Informatics and Bioinformatics, 2019, 8
  • [3] DeCoaD: Determining correlations among diseases using protein interaction networks
    Hamaneh M.B.
    Yu Y.-K.
    [J]. BMC Research Notes, 8 (1)
  • [4] Identification of target genes in cancer diseases using protein-protein interaction networks
    Amala, Arumugam
    Emerson, Isaac Arnold
    [J]. NETWORK MODELING AND ANALYSIS IN HEALTH INFORMATICS AND BIOINFORMATICS, 2019, 8 (01):
  • [5] Discovery of protein interaction networks shared by diseases
    Sam, Lee
    Liu, Yang
    Li, Jianrong
    Friedman, Carol
    Lussier, Yves A.
    [J]. PACIFIC SYMPOSIUM ON BIOCOMPUTING 2007, 2007, : 76 - +
  • [6] Using virtual reality to understand complex metabolic networks
    Dickerson, JA
    Yang, Y
    Blom, K
    Reinot, A
    Lie, J
    Cruz-Neira, C
    Wurtele, ES
    [J]. PROCEEDINGS OF THE 7TH JOINT CONFERENCE ON INFORMATION SCIENCES, 2003, : 950 - 953
  • [7] PEPPER: cytoscape app for protein complex expansion using protein-protein interaction networks
    Winterhalter, C.
    Nicolle, R.
    Louis, A.
    To, C.
    Radvanyi, F.
    Elati, M.
    [J]. BIOINFORMATICS, 2014, 30 (23) : 3419 - 3420
  • [8] DIGNiFI: Discovering causative genes for orphan diseases using protein-protein interaction networks
    Liu, Xiaoxia
    Yang, Zhihao
    Lin, Hongfei
    Simmons, Michael
    Lu, Zhiyong
    [J]. PROCEEDINGS OF THE 7TH ACM INTERNATIONAL CONFERENCE ON BIOINFORMATICS, COMPUTATIONAL BIOLOGY, AND HEALTH INFORMATICS, 2016, : 527 - 527
  • [9] DIGNiFI: Discovering causative genes for orphan diseases using protein-protein interaction networks
    Liu, Xiaoxia
    Yang, Zhihao
    Lin, Hongfei
    Simmons, Michael
    Lu, Zhiyong
    [J]. BMC SYSTEMS BIOLOGY, 2017, 11
  • [10] Human protein interaction networks across tissues and diseases
    Yeger-Lotem, Esti
    Sharan, Roded
    [J]. FRONTIERS IN GENETICS, 2015, 6