Angular Domain Spectroscopic Imaging of Turbid Media: Derivative Analysis

被引:0
|
作者
Vasefi, Fartash [1 ,2 ,3 ]
Najiminaini, Mohamadreza [1 ,3 ]
Ng, Eldon [1 ,2 ]
Chamson-Reig, Astrid [1 ]
Kaminska, Bozena [3 ]
Carson, Jeffrey J. L. [1 ,2 ]
机构
[1] Lawson Hlth Res Inst, Imaging Program, London, ON, Canada
[2] Univ Western Ontario, Schulich Sch Med & Dent, Med Biophys, London, ON, Canada
[3] Simon Fraser Univ, Sch Engn Sci, Burnaby, BC, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
Hyperspectral imaging; spectroscopy in turbid media; analytical spectroscopy; micromachining angular filters; OPTICAL PROJECTION TOMOGRAPHY; CONTRAST; CANCER;
D O I
10.1117/12.874351
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Angular Domain Spectroscopic Imaging employs an array of micro-channels to perform angular filtering of light that traverses a turbid sample to reject moderately to highly scattered light. In this work, we experimentally characterized an ADSI system by measuring transmission spectra and the first and second derivatives obtained from absorbing and scattering targets. The derivative analysis was used to estimate the concentration of indocyanine green mixed in a scattering liquid. The experimental results provided support for ADSI as a potential method for quantitative spectroscopic imaging of ex vivo tissue samples.
引用
收藏
页数:8
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