Preparation of cellulose nanofibril/titanium dioxide nanoparticle nanocomposites as fillers for PVA-based packaging and investigation into their intestinal toxicity
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作者:
Yu, Zhilong
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Univ Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USAUniv Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USA
Yu, Zhilong
[1
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Wang, Wei
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Univ Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USAUniv Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USA
Wang, Wei
[1
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Sun, Lin
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Univ Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USAUniv Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USA
Sun, Lin
[1
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Kong, Fanbin
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Univ Georgia, Dept Food Sci & Technol, Athens, GA 30602 USAUniv Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USA
Kong, Fanbin
[2
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Lin, Mengshi
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Univ Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USAUniv Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USA
Lin, Mengshi
[1
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Mustapha, Azlin
[1
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机构:
[1] Univ Missouri, Div Food Syst & Bioengn, Food Sci Program, Columbia, MO 65211 USA
[2] Univ Georgia, Dept Food Sci & Technol, Athens, GA 30602 USA
The aims of this work were to synthesize cellulose nanofibril/titanium dioxide nanoparticle (CNF/TiO2NP) nanocomposites, evaluate the use of CNF/TiO2NP nanocomposites in PVA-based films, and investigate the intestinal toxicity of the nanocomposites. Via a mixing method, CNF/TiO2NP nanocomposites were synthesized. The addition of the nanocomposites significantly enhanced the tensile strength, Young's modulus, and light barrier capacity of PVA films. Moreover, a high concentration of CNF/TiO2NP nanocomposites (10 mg/mL) had no appreciable effect on the growth of Escherichia colt P-24, Lactobacillus acidophilus ADEL and Bifidobacterium animalis Bif-6 cells. The nanocomposites did not exhibit significant toxicity to cancerous and normal colon cells even when their concentrations increased to a high level of 1000 mu g/mL. The results indicate that CNF/TiO2NP nanocomposites can potentially be used as functional fillers for a PVA-based packaging system. (C) 2019 Elsevier B.V. All rights reserved.