Recombinant human factor VIIa in the management of amyloid-associated factor X deficiency

被引：40
|
作者：
Boggio, L [1 ]
Green, D [1 ]
机构：
[1] Northwestern Univ, Sch Med, Dept Med, Div Hematol Oncol, Chicago, IL 60611 USA
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2001年 / 112卷 / 04期
关键词：
amyloid; factor X deficiency; rccombinant factor; operation is problematic VIIa; splenectomy; haemostasis;
D O I：
10.1046/j.1365-2141.2001.02667.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Factor X deficiency is an important complication of amyloidosis. It is associated with severe bleeding that is difficult to control with plasma or prothrombin complex concentrates. Splenectomy ameliorates the factor X deficiency, but achieving satisfactory haemostasis for this operation is problematic. We report that a new clotting concentrate, recombinant factor VIIa, readily controls bleeding and makes splenectomy feasible.
引用
收藏
页码：1074 / 1075
页数：2
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