Unusual radical addition on a heteroaromatic nitrogen. A convenient access to new pyrimidine derivatives

被引：19
|
作者：
Laot, Yann [1 ]
Petit, Laurent [1 ]
Zard, Samir Z. [1 ]
机构：
[1] Ecole Polytech, CNRS, UMR 7652, Synth Organ Lab, F-91128 Palaiseau, France
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 31期
关键词：
INHIBITORS; PROTEIN; AGENTS;
D O I：
10.1039/c0cc00533a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A radical generated on the side-chain of a 2- or 4-N-alkylamino-4,6- or 2,6-dichloropyrimidine can cyclise on the nitrogen or on the carbon of the pyrimidine ring depending on its position and on whether an acetyl or a Boc group is present on the extranuclear nitrogen.
引用
收藏
页码：5784 / 5786
页数：3
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