Rabeprazole: A proton pump inhibitor for the treatment of acid-related disorders

Rabeprazole is a proton pump inhibitor that exhibits potent gastric acid suppression through inhibition of the H+/K+ ATPase pump. In clinical trials, rabeprazole has been shown to be safe and effective for the treatment of both gastric and duodenal ulcers, as well as gastroesophageal reflux disease. Rabeprazole also has been shown to have activity against Helicobacter pylori, In comparative trials with omeprazole, rabeprazole was found to be equally effective in the treatment of these disorders, with evidence of superior symptomatic relief and a quicker onset of action. The drug has a convenient once-daily dosing schedule and a side effect profile comparable to those of the other proton pump inhibitors. Rabeprazole gives clinicians another safe and effective option for the treatment of acid-related disorders.