Bottom-up approach to build osteon-like structure by cell-laden photocrosslinkable hydrogel

被引：27

作者：

Zuo, Yicong ^{[1
]}

Xiao, Wenqian ^{[1
]}

Chen, Xiaoqin ^{[1
]}

Tang, Yajun ^{[1
]}

Luo, Hongrong ^{[1
]}

Fan, Hongsong ^{[1
]}

机构：

[1] Sichuan Univ, Natl Engn Res Ctr Biomat, Chengdu 610064, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 26期

基金：

中国国家自然科学基金;

关键词：

OSTEOGENIC DIFFERENTIATION; TISSUE; CONSTRUCTS; MICROSCALE; SURFACES;

D O I：

10.1039/c2cc16744a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Based on photocrosslinkable PEGDMA and GelMA hydrogels, two "bottom-up" approaches ("circle-and-cross" and "layer-by-layer") were successfully developed to construct osteon-like structures with microchannel networks. Significantly, the "layer-by-layer" approach employing the GelMA hydrogel with a higher biocompatibility was more favorable for building biomimetic osteon.

引用

页码：3170 / 3172

页数：3

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