Medicine acceptability for older people in hospital and care home: the influence of setting

被引:3
|
作者
Jani, Yogini H. [1 ,2 ]
Liu, Fang [3 ]
Orlu, Mine [4 ]
Desai, Neel [4 ]
du Chayla, Florence [5 ]
Ruiz, Fabrice [5 ]
Vallet, Thibault [5 ]
机构
[1] UCLH NHS Fdn Trust, Ctr Med Optimisat Res & Educ, 235 Euston Rd, London NW1 2BU, England
[2] UCL Sch Pharm, London, England
[3] Univ Hertfordshire, Dept Clin Pharmaceut & Biol Sci, Hatfield, Herts, England
[4] UCL, UCL Sch Pharm, London, England
[5] ClinSearch, Malakoff, France
基金
英国工程与自然科学研究理事会;
关键词
medicine; acceptability; older population; swallowing disorders; solid oral dosage form; MEDICATION; DYSPHAGIA; SWALLOWABILITY; PALATABILITY; RESIDENTS; ADHERENCE; DISEASE; ERRORS;
D O I
10.1093/ijpp/riab077
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Objective Medicines acceptability is likely to have a significant impact on older people's adherence and, consequently, treatment effectiveness. The objective was to explore the influence of setting on medicines acceptability in older people. Methods A multi-centre, prospective, cross-sectional, observational study was conducted in one care home and one elderly care hospital ward in London, UK, involving individuals on =1 medicine(s) and aged >= 65 years. Data-driven approach was applied using multiple observer-reported outcomes analysis tool to distinguish between positively and negatively accepted medicines. Key findings 263 observer reports from the care home (n = 97) and hospital ward (n = 166) involving 155 distinct medicinal products were assessed. Collectively, medicines appeared better accepted by patients at the hospital. Differences appeared to be driven by variations in solid oral dosage form (SODF) acceptability. Patients with dysphagia poorly accepted medicines in both settings, as expected. SODFs were unexpectedly better accepted in the hospital than in the care home in patients without dysphagia. Conclusions Medicines acceptability was affected by patient's characteristics, dosage form type and setting. Changes in care practices between care home and hospital may affect medicine administration and lead to variations in the ability and willingness of patients and carers to use the product as intended.
引用
收藏
页码:67 / 74
页数:8
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