Synthesis of thiazole, benzothiazole, oxadiazole, thiadiazole, triazole and thiazolidinone incorporated coumarins

3-Bromoacetylcoumarin-(2) obtained by bromination of 3-acetylcoumarin (1) was condensed with 2-amino-4-phenylthiazole, 2-aminothiazole, 2-aminobenzothiazole, 2-amino-4-phenyloxadiazole, 2-aminothiadiazole, 3-aminotriazole to form the corresponding heteroaryl aminoacetylcoumarins (3a-f). The reaction of 2 with thiourea furnished 2-amino-4-(coumarinyl-3) thiazole (4) which further reacted with phenylisothiocyanate forming the unsymmetrical thiourea (5). The thiourea on cyclocondensation with chloroacetic acid gave the thiazolidinone (6) which on further reaction with different aromatic aldehydes resulted in the formation of the corresponding arylidene compounds (7). The structures of the products were confirmed from their analytical and spectral data.