Drug-Induced Hypertension

被引：23

作者：

Foy, Matthew C. ^{[1
]}

Vaishnav, Joban ^{[2
]}

Sperati, Christopher John ^{[3
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Div Nephrol, 5246 Brittany Dr, Baton Rouge, LA 70808 USA

[2] Johns Hopkins Univ, Sch Med, Div Cardiol, 600 N Wolfe St, Baltimore, MD 21287 USA

[3] Johns Hopkins Univ, Sch Med, Div Nephrol, 1830 East Monument St,Room 416, Baltimore, MD 21287 USA

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2019年 / 48卷 / 04期

关键词：

Drug-induced hypertension; Secondary hypertension; Polypharmacy; ENDOTHELIAL GROWTH-FACTOR; KIDNEY-TRANSPLANT RECIPIENTS; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; ANGIOTENSIN SYSTEM BLOCKADE; BLOOD-PRESSURE; NITRIC-OXIDE; ARTERIAL-HYPERTENSION; ORAL-CONTRACEPTIVES; RENAL-FUNCTION; ERYTHROPOIETIN;

D O I：

10.1016/j.ecl.2019.08.013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Untoward side effects of pharmaceuticals can result in considerable morbidity and expense to the health care system. There is likely a sizable fraction of the hypertensive population with disease either induced or exacerbated by polypharmacy. The elevation of blood pressure in drug-induced hypertension occurs through a variety of mechanisms, most notably, sodium and fluid retention, activation of the renin-angiotensin-aldosterone system, alteration of vascular tone, or a combination of these pathways. Recognition of common medications causing drug-induced hypertension is important to effectively control blood pressure. The epidemiology, pathophysiology, and management of these agents are discussed.

引用

页码：859 / +

页数：16

共 50 条

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