A POLYMER-DRUG SYSTEM BASED ON REGENERATED CELLULOSE USED IN TEXTILE INDUSTRY

Biocompatible absorptive materials with porous structure, formed by cavities with different sizes, have many medical applications, such as drug carriers, base for cell regeneration, implants for tissue regeneration. The immobilization of synthesized indazole derivatives with germicidal, aseptic and anti-inflammatory activity, by diffusion into a regenerated cellulose matrix is studied. The theological properties of the new composite material are studied, considering the mechanical properties of the materials with potential use in shoe manufacturing for diabetic foot diseases. The immobilization of indazole derivatives onto the cellulose matrix is influenced by certain parameters, like the derivatives/cellulose ratio and cavity structure of the cellulose matrix. New polymer-drug blend systems with medical benefits were obtained and the most important physicomechanical properties of the new composite, such as water retention and tensile strength, were studied.