Nonalcoholic Fatty Liver Disease

被引:41
|
作者
Sweet, Patrick H. [1 ]
Khoo, Teresa [2 ]
Nguyen, Steven [2 ]
机构
[1] Univ Calif Riverside, Family Med, 555 Tachevah Dr,2E-204, Palm Springs, CA 92262 USA
[2] Univ Calif Riverside, Family Med Residency Palm Springs, 555 Tachevah Dr,2E-204, Palm Springs, CA 92262 USA
来源
PRIMARY CARE | 2017年 / 44卷 / 04期
关键词
Nonalcoholic fatty liver disease (NAFLD); Nonalcoholic steatohepatitis (NASH); Liver disease; Metabolic disease; Dyslipidemia; Insulin resistance; Steatosis; DIAGNOSIS;
D O I
10.1016/j.pop.2017.07.003
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Nonalcoholic fatty liver disease (NAFLD) defines a condition of hepatic steatosis with or without hepatic injury. NAFLD is increasing in prevalence worldwide and presents a public health burden. Most patients are asymptomatic, although some present with fatigue and right upper quadrant pain. NAFLD is discovered incidentally when patients have elevated liver enzymes or fatty liver is seen on imaging modalities. Imaging studies can confirm fatty deposits in the liver, but needle biopsy is needed to determine the degree of inflammation. The mainstay of treatment is weight loss and controlling diabetes and hyperlipidemia. Liver transplantation is considered when disease progresses to cirrhosis.
引用
收藏
页码:599 / +
页数:11
相关论文
共 50 条
  • [1] Nonalcoholic Fatty Liver Disease Is Related to Nonalcoholic Fatty Pancreas Disease
    van Geenen, Erwin-Jan M.
    Smits, Mark M.
    Schreuder, Tim C. M. A.
    van der Peet, Donald L.
    Bloemena, Elisabeth
    Mulder, Chris J. J.
    [J]. PANCREAS, 2010, 39 (08) : 1185 - 1190
  • [2] Nonalcoholic fatty liver disease
    Alfie, ME
    Treem, WR
    [J]. PEDIATRIC ANNALS, 2006, 35 (04): : 290 - +
  • [4] Nonalcoholic fatty liver disease
    Bayard, Max
    Holt, Jim
    Boroughs, Eileen
    [J]. AMERICAN FAMILY PHYSICIAN, 2006, 73 (11) : 1961 - 1968
  • [5] Nonalcoholic fatty liver disease
    Clark, JM
    Brancati, FL
    Diehl, AM
    [J]. GASTROENTEROLOGY, 2002, 122 (06) : 1649 - 1657
  • [6] Nonalcoholic Fatty Liver Disease
    Wang, Xiao Jing
    Malhi, Harmeet
    [J]. ANNALS OF INTERNAL MEDICINE, 2018, 169 (09) : ITC65 - ITC80
  • [7] Nonalcoholic Fatty Liver Disease
    Fitzgerald, Margaret A.
    [J]. NURSE PRACTITIONER, 2007, 32 (02): : 6 - 7
  • [8] Nonalcoholic fatty liver disease
    Elizabeth M. Brunt
    Vincent W.-S. Wong
    Valerio Nobili
    Christopher P. Day
    Silvia Sookoian
    Jacquelyn J. Maher
    Elisabetta Bugianesi
    Claude B. Sirlin
    Brent A. Neuschwander-Tetri
    Mary E. Rinella
    [J]. Nature Reviews Disease Primers, 1
  • [9] Nonalcoholic fatty liver disease
    Madan, P
    [J]. CANADIAN MEDICAL ASSOCIATION JOURNAL, 2005, 173 (07) : 734 - 735
  • [10] Nonalcoholic Fatty Liver Disease
    Filipovic, Branka
    Forbes, Alastair
    Tepes, Bojan
    Dumitrascu, Dan L.
    [J]. CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2018, 2018