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- [7] JS']JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells BRITISH JOURNAL OF HAEMATOLOGY, 2006, 135 (01) : 26 - 32