The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease

被引：43
|
作者：
Maschke, M
Tuite, PJ
Pickett, K
Wächter, T
Konczak, J
机构：
[1] Univ Essen Gesamthsch, Dept Neurol, D-45122 Essen, Germany
[2] Univ Minnesota, Div Kinesiol, Sensorimotor Control Lab, Minneapolis, MN USA
[3] Univ Minnesota, Minneapolis VAMC, Brain Sci Ctr, Minneapolis, MN USA
来源：
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2005年 / 76卷 / 04期
关键词：
D O I：
10.1136/jnnp.2004.047324
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background: Parkinson's disease is accompanied by deficits in passive motion and limb position sense. Objective: To investigate whether deep brain stimulation of the subthalamic nucleus (STN-DBS) reverses these proprioceptive deficits. Methods and results: A passive movement task was applied to nine patients with Parkinson's disease and bilateral chronic STN-DBS and to seven controls. Thresholds for 75% correct responses were 0.9 degrees for controls, 2.5 degrees for Parkinson's disease patients when stimulation was OFF, and 2.0 degrees when stimulation was ON. Conclusions: STN-DBS improves kinaesthesic deficits in Parkinson's disease, but does not lead to a full recovery a proprioceptive function.
引用
收藏
页码：569 / 571
页数：3
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