Sequential cyclizations of 2-Isothiocyanatobenzonitrile with α-amino-carboxylic esters and acids

被引：9
|
作者：
Langer, P [1 ]
Bodtke, A [1 ]
机构：
[1] Ernst Moritz Arndt Univ Greifswald, Inst Chem & Biochem, D-17487 Greifswald, Germany
来源：
SYNLETT | 2003年 / 11期
关键词：
amino acids; cyclizations; domino reactions; isothiocyanates; regioselectivity;
D O I：
10.1055/s-2003-41435
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The cyclization of 2-isothiocyanatobenzonitrile with alpha-aminocarboxylic esters and acids afforded a variety of 2-oxo-2,3,5,6-tetrahydro-5-thioxo-imidazo[1,2-c]quinazolines with very good regioselectivity.
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页码：1743 / 1745
页数：3
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