Synthesis of spiro 2-(5-amino-2,3-dihydro-3-oxopyrrol-4-yl)-1,3-dialkylbenzimidazolium chlorides

被引：0
|
作者：
Dobrydnev, Alexey V. [1 ,2 ]
Volovenko, Yulian M. [1 ]
Turov, Alexandr V. [1 ]
Medviediev, Volodymyr V. [3 ]
Shishkin, Oleg V. [3 ,4 ]
Volovnenko, Tatyana A. [1 ]
机构：
[1] Taras Shevchenko Natl Univ Kiev, Dept Chem, UA-01601 Kiev, Ukraine
[2] State Ctr Innovat Biotechnol, UA-03151 Kiev, Ukraine
[3] Natl Acad Sci Ukraine, Div Funct Mat Chem, SSI Inst Single Crystals, UA-61001 Kharkov, Ukraine
[4] Kharkov Natl Univ, Dept Inorgan Chem, UA-61202 Kharkov, Ukraine
来源：
MONATSHEFTE FUR CHEMIE | 2015年 / 146卷 / 06期
关键词：
Pyrroles; Cyclization; Spiro compounds; Antitumor agents; Lanthanide shift reagent; X-ray structure determination;
D O I：
10.1007/s00706-015-1438-3
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The interaction of 1,3-dialkyl-2,3-dihydro-1H-benzo[d]imidazol-2-ylidenemethyl cyanides with N-trifluoroacylated acid chlorides gave the desired (3-cyano-2-oxo-3-hetarylpropyl)-2,2,2-trifluoroacetamides that upon detrifluoroacetylation provided the target 2-(5-amino-2,3-dihydro-3-oxopyrrol-4-yl)-1,3-dialkylbenzimidazolium chlorides. [GRAPHICS]
引用
收藏
页码：931 / 939
页数：9
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