COVID-19 in a Cohort of Patients with Congenital Myasthenic Syndrome

被引:2
|
作者
Alabaf, Setareh [1 ,2 ]
O'Connell, Karen [1 ]
Ramdas, Sithara [1 ]
Beeson, David [1 ,2 ]
Palace, Jacqueline [1 ]
机构
[1] Univ Oxford, Nuffield Dept Clin Neurosci, Oxford OX3 9DU, England
[2] Univ Oxford, John Radcliffe Hosp, Weatherall Inst Mol Med, Neurosci Grp, Oxford, England
关键词
COVID-19; congenital myasthenic syndrome; neuromuscular disorders; clinical outcome;
D O I
10.3233/JND-210699
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Congenital Myasthenic Syndromes (CMS) are a rare group of genetic disorders of neuromuscular transmission. Some subtypes of CMS can be associated with respiratory and bulbar weakness and these patients may therefore be at high risk of developing a severe disease from COVID-19. We screened 73 patients with genetically confirmed CMS who were attending the UK national referral centre for evidence of previous Severe Acute Respiratory Syndrome Corona Virus 2 infection and their clinical outcome. Of 73 patients, seven had history of confirmed COVID-19. None of the infected patients developed a severe disease, and there were no signals that CMS alone carries a high risk of severe disease from COVID-19.
引用
收藏
页码:1003 / 1005
页数:3
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