Current and Emerging Approaches for Hepatic Fibrosis Treatment

被引：11
|
作者：
Li, Jingguo [1 ]
Tuo, Biguang [1 ]
机构：
[1] Zunyi Med Univ, Affiliated Hosp, Dept Gastroenterol, Zunyi, Guizhou, Peoples R China
来源：
GASTROENTEROLOGY RESEARCH AND PRACTICE | 2021年 / 2021卷
基金：
中国国家自然科学基金;
关键词：
ENDOTHELIAL PROGENITOR CELLS; MESENCHYMAL STEM-CELLS; FECAL MICROBIOTA TRANSPLANTATION; PLACEBO-CONTROLLED TRIAL; CHRONIC LIVER-DISEASE; X RECEPTOR AGONIST; BONE-MARROW-CELLS; NONALCOHOLIC STEATOHEPATITIS; VITAMIN-E; PORTAL-HYPERTENSION;
D O I：
10.1155/2021/6612892
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Liver fibrosis resulting from chronic liver injury is a key factor to develop liver cirrhosis and risk of hepatocellular carcinoma (HCC) which are major health burden worldwide. Therefore, it is necessary for antifibrotic therapies to prevent chronic liver disease progression and HCC development. There has been tremendous progress in understanding the mechanisms of liver fibrosis in the last decade, which has created new opportunities for the treatment of this condition. In this review, we aim to make an overview on information of different potential therapies (drug treatment, cell therapy, and liver transplantation) for the liver fibrosis and hope to provide the therapeutic options available for the treatment of liver fibrosis and discuss novel approaches.
引用
收藏
页数：13
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