New anti-inflammatory steroids from the Formosan soft coral Clavularia viridis

被引：21
|
作者：
Chang, Chin-Hsiang [2 ]
Wen, Zhi-Hong [1 ,2 ]
Wang, Shang-Kwei [3 ]
Duh, Chang-Yih [1 ,2 ]
机构：
[1] Natl Sun Yat Sen Univ, Ctr Asia Pacific Marine Res, Kaohsiung 804, Taiwan
[2] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 80424, Taiwan
[3] Kaohsiung Med Univ, Dept Microbiol, Kaohsiung, Taiwan
来源：
STEROIDS | 2008年 / 73卷 / 05期
关键词：
steroids; Clavularia viridis; anti-inflammatory activity;
D O I：
10.1016/j.steroids.2008.01.007
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Four new steroids, stoloniferones R-T (1-3), and (25S)-24-methylenecholestane-3 beta,5 alpha,6 beta-triol-26-acetate (4) were isolated from the methylene chloride solubles of the soft coral Clavularia viridis. The structures of the metabolites were elucidated by extensive spectral analysis and their anti-inflammatory activity was measured in vitro. (C) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码：562 / 567
页数：6
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