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Clonal spread of pediatric isolates of ciprofloxacin-resistant, emm type 6 Streptococcus pyogenes
被引:7
|作者:
Alonso, R
Mateo, E
Galimand, M
Garaizar, J
Courvalin, P
Cisterna, R
机构:
[1] Univ Basque Country, Fac Farm, Dept Inmunol Microbiol & Parasitol, Vitoria 01006, Spain
[2] Inst Pasteur, Unite Agents Antibacteriens, F-75724 Paris, France
[3] Hosp Basurto, Serv Microbiol, Bilbao 48013, Spain
关键词:
D O I:
10.1128/JCM.43.5.2492-2493.2005
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
Twenty-four community isolates of Streptococcus pyogenes resistant to ciprofloxacin and susceptible to levofloxacin, gatifloxacin, and moxifloxacin were studied. Sequence determination of the quinolone resistance-determining regions in the gyrA and parC genes revealed a T/G mutation in parC leading to a Ser79AIa substitution in ParC. All isolates were of the emm type 6, and 18 and 2 of them were indistinguishable or closely related, respectively, on the basis of pulsed-field gel electrophoresis.
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页码:2492 / 2493
页数:2
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