Metabolomics studies of chronic atrophic gastritis cold and heat syndrome

The objective of this work is to study the specific plasma metabolites of chronic atrophic gastritis cold and heat syndrome, an d search the relevance pattern with cold-heat syndrome. Collect general data and blood samples of chronic atrophic gastritis cold- heat syndrome patients through clinical cross-sectional investigation, and resort GC-MS analytic technique to analyze the patient's metabolites and change of corresponding metabolites spectrum group. Then use many kinds of data-mining methods to discuss the corresponding relation between cold-heat syndrome and specific metabolites. The true positive rate of this decision tree modeling is 81.5 %, which is established by compounds whose retention time are 33.16, 21.83, 33.26, 34.69. chronic atrophic gastritis cold and heat syndrome will produce specific metabolites that may provide an objective basis for judging cold-heat syndrome. Accordingly, new ideas and methods are provided for pattern identification of traditional Chinese medicine (TCM) and deep research on symptoms.