AMP579, an adenosine A1 and A2A receptor agonist, limits infarct size in rabbit heart in vivo when given at reperfusion:: Role of A2A receptor activation

被引：0
|
作者：
Baxter, GF [1 ]
Kis, A [1 ]
Yellon, DM [1 ]
机构：
[1] UCL Hosp & Med Sch, Hatter Inst, London WC1E 6DB, England
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 2001年 / 133卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
8P
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Limitation of Myocardial Reperfusion Injury by AMP579, an Adenosine A1/A2A Receptor Agonist: Role of A2A Receptor and Erk1/2
    Adrienn Kis
    Gary F. Baxter
    Derek M. Yellon
    Cardiovascular Drugs and Therapy, 2003, 17 : 415 - 425
  • [2] Limitation of myocardial reperfusion injury by AMP579, an adenosine A1/A2A receptor agonist:: Role of A2A receptor and Erk1/2
    Kis, A
    Baxter, GF
    Yellon, DM
    CARDIOVASCULAR DRUGS AND THERAPY, 2003, 17 (5-6) : 415 - 425
  • [3] The adenosine A1/A2a receptor agonist AMP579 attenuates in vivo myocardial stunning without hemodynamic effects
    Stevens, RM
    Jahania, MS
    Klar, BM
    Mentzer, RM
    Lasley, RD
    CIRCULATION, 2002, 106 (19) : 96 - 96
  • [4] Amp579, an A1/A2a agonist, limits infarct size at reperfusion via a p42/p44 MAPK-dependent pathway
    Baxter, GF
    Ebrahim, Z
    Yellon, DM
    CIRCULATION, 2000, 102 (18) : 212 - 212
  • [5] AMP579, an adenosine A1 and A2A receptor agonist, attenuates lethal reperfusion injury in rat heart via the p42/p44 MAPK pathway
    Baxter, GF
    Ebrahim, Z
    Yellon, DM
    BRITISH JOURNAL OF PHARMACOLOGY, 2001, 133
  • [6] Efficient synthesis of AMP579, a novel adenosine A1/A2 receptor agonist
    Sledeski, AW
    Kubiak, GG
    O'Brien, MK
    Powers, MR
    Powner, TH
    Truesdale, LK
    JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (23): : 8114 - 8118
  • [7] Adenosine A1/A2a receptor agonist AMP-579 induces acute and delayed preconditioning against in vivo myocardial stunning
    Kristo, G
    Yoshimura, Y
    Keith, BJ
    Stevens, RM
    Jahania, SA
    Mentzer, RM
    Lasley, RD
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2004, 287 (06): : H2746 - H2753
  • [8] Pharmacological characterization of AMP579, a novel A1/A2 adenosine receptor agonist and cardioprotective
    Merkel, L
    Hawkins, ED
    Colussi, DJ
    Rossi, D
    Rojas, CJ
    Hamel, LT
    Jarvis, MF
    Fink, C
    Studt, RW
    Spada, AP
    Clark, KL
    Perrone, MH
    FASEB JOURNAL, 1998, 12 (04): : A78 - A78
  • [9] Limitation of infarct size in rabbit hearts by the novel adenosine receptor agonist AMP 579 administered at reperfusion
    Xu, ZL
    Yang, XM
    Cohen, MV
    Neumann, T
    Heusch, G
    Downey, JM
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2000, 32 (12) : 2339 - 2347
  • [10] AMP-579.: Treatment of acute myocardial infarction, adenosine A1/A2A agonist
    Sorbera, LA
    Martín, L
    Leeson, PA
    Castañer, J
    DRUGS OF THE FUTURE, 2000, 25 (09) : 900 - 906
12345