Ferrocene-functionalized cationic polythiophene for the label-free electrochemical detection of DNA

被引：88
|
作者：
Le Floch, F
Ho, HA
Harding-Lepage, P
Bédard, M
Neagu-Plesu, R
Leclerc, M [1 ]
机构：
[1] Univ Laval, Canada Res Chair Electroact & Photoact Polymers, Dept Chim, Quebec City, PQ G1K 7P4, Canada
[2] Univ Laval, CERSIM, Dept Chim, Quebec City, PQ G1K 7P4, Canada
来源：
ADVANCED MATERIALS | 2005年 / 17卷 / 10期
关键词：
D O I：
10.1002/adma.200401474
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Specific, sensitive detection of unlabeled target DNA at room temperature is reported. A new, water-soluble, ferrocene-functionalized, cationic polythiophene is synthesized. This conducting polymer, used together with gold-bound peptide nucleic acid (PNA) probes, makes, by a simple electrostatic method, DNA detection possible (see Figure).
引用
收藏
页码：1251 / +
页数：5
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