Effects of sidestream cigarette smoke exposure on baroreflex components in spontaneously hypertensive rats

被引：14

作者：

Valenti, Vitor E. ^{[1
]}

Abreu, Luiz Carlos ^{[2
]}

Saldiva, Paulo H. ^{[3
]}

Carvalho, Tatiana D. ^{[1
]}

Ferreira, Celso ^{[1
]}

机构：

[1] Univ Fed Sao Paulo UNIFESP, Dept Med, Disciplina Cardiol, Sao Paulo, Brazil

[2] ABC, Fac Med, Dept Morfol & Fisiol, Santo Andre, Brazil

[3] Univ Sao Paulo, Dept Patol, Sao Paulo, Brazil

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH | 2010年 / 20卷 / 06期

基金：

巴西圣保罗研究基金会;

关键词：

tobacco; baroreflex; air pollutants; smoke; ENVIRONMENTAL TOBACCO-SMOKE; CARDIOMYOCYTES NUCLEAR SIZE; LONG-TERM EXPOSURE; VENTRICLE;

D O I：

10.1080/09603123.2010.491852

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

We evaluated short-term effects of sidestream cigarette smoke (SSCS) exposure on baroreflex function in spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) normotensive rats. Rats were exposed to SSCS during three weeks, 180min, five days per week, in a concentration of carbon monoxide (CO) between 100 and 300ppm. We observed that SSCS exposure increased tachycardic peak and heart rate range while it attenuated bradycardic reflex in WKY. In respect to SHR, SSCS also increased tachycardic peak. Taken together, our data suggests that three weeks of exposure to SSCS affects the sympathetic and parasympathetic component of the baroreflex in normotensive WKY while it tended to affect the sympathetic component in SHR.

引用

页码：431 / 437

页数：7

共 50 条

[1] Sidestream Cigarette Smoke Exposure Effects on Baroreflex in Adult Rats
Valenti, Vitor E.
de Abreu, Luiz Carlos
Ferreira, Celso
[J]. ARQUIVOS BRASILEIROS DE CARDIOLOGIA, 2011, 96 (02) : 148 - 153
[2] Pharmacodynamic effects of chronic cigarette smoke exposure in spontaneously hypertensive rats
Tanaka, T
Ohno, N
Kita, T
Kubo, K
Yonetani, Y
Nakashima, T
[J]. METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY, 2004, 26 (01): : 9 - 18
[3] Effects of the administration of a catalase inhibitor into the fourth cerebral ventricle on cardiovascular responses in spontaneously hypertensive rats exposed to sidestream cigarette smoke
Valenti, Vitor E.
de Abreu, Luiz Carlos
Fonseca, Fernando L. A.
Adami, Fernando
Sato, Monica A.
Vanderlei, Luiz Carlos M.
Ferreira, Lucas Lima
Rodrigues, Luciano M.
Ferreira, Celso
[J]. CLINICS, 2013, 68 (06) : 851 - 857
[4] Inflammation and morphometric changes in the lungs of spontaneously hypertensive rats following cigarette smoke exposure
Vanscheeuwijck, P.
Meurrens, K.
Van Miert, E.
Friedrichs, B.
Weiler, H.
[J]. TOXICOLOGIC PATHOLOGY, 2007, 35 (01) : 180 - 180
[5] EFFECT OF EXPOSURE TO CIGARETTE SIDESTREAM SMOKE ON GROWTH IN YOUNG-RATS
TACHI, N
AOYAMA, M
[J]. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1988, 40 (04) : 590 - 596
[6] Microbiological components in mainstream and sidestream cigarette smoke
Larsson, Lennart
Pehrson, Christina
Dechen, Tenzin
Crane-Godreau, Mardi
[J]. TOBACCO INDUCED DISEASES, 2012, 10
[7] Action of endothelins relates to pharmacodynamic effects of chronic cigarette smoke in spontaneously hypertensive rats
Ohno, N
Kubo, K
Kita, T
Tanaka, T
Yonetani, Y
Konishi, N
Nakashima, T
[J]. JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004, 94 : 211P - 211P
[8] CENTRAL EFFECTS OF ENDOTHELIN ON BAROREFLEX OF SPONTANEOUSLY HYPERTENSIVE RATS
VANDENBUUSE, M
ITOH, S
[J]. JOURNAL OF HYPERTENSION, 1993, 11 (04) : 379 - 387
[9] Perinatal sidestream cigarette smoke exposure and the developing pulmonary surfactant system in rats
Subramaniam, S
Srinivasan, S
Bummer, PM
Gairola, CG
[J]. HUMAN & EXPERIMENTAL TOXICOLOGY, 1999, 18 (04) : 206 - 211
[10] GENOTOXIC AND EMBRYOTOXIC EFFECTS OF CIGARETTE SIDESTREAM SMOKE ON LABORATORY MICE AND RATS
MOHTASHAMIPUR, E
NORPOTH, K
KEMPA, K
STRATER, H
[J]. ZENTRALBLATT FUR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE SERIE B-UMWELTHYGIENE KRANKENHAUSHYGIENE ARBEITSHYGIENE PRAVENTIVE MEDIZIN, 1987, 184 (05): : 447 - 447

← 1 2 3 4 5 →