A method for synthesis of gold nanoparticles using 1-amino-2-naphthol-4-sulphonic acid as reducing agent

被引:5
|
作者
Rawat, Pooja [1 ]
Rajput, Y. S. [1 ]
Bharti, Mahesh K. [1 ]
Sharma, Rajan [2 ]
机构
[1] ICAR Natl Dairy Res Inst, Anim Biochem Div, Karnal 132001, India
[2] ICAR Natl Dairy Res Inst, Dairy Chem Div, Karnal 132001, India
来源
CURRENT SCIENCE | 2016年 / 110卷 / 12期
关键词
Gold nanoparticles; immunoglobulins; lateral flow assay; reducing agent; COLLOIDAL GOLD; SILVER;
D O I
10.18520/cs/v110/i12/2297-2300
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The present communication describes the synthesis of gold nanoparticles (AuNPs) using 1-amino-2-naphthol-4-sulphonic acid (ANSA) with enhanced stability. The method of preparation is similar to the conventional method using sodium citrate as reducing agent. Briefly, ANSA was quickly added to a boiled solution of hydrogen tetrachloroaurate under stirring, resulting in the synthesis of deep red-coloured AuNPs. The AuNPs prepared by ANSA (AuNPs-ANSA) exhibit twofold increase in stability towards sodium chloride over those prepared by sodium citrate. AuNPs-ANSA are 35.1 nm in size and particles has various shapes, viz. hexagonal, pentagonal, spherical, etc. AuNPs-ANSA can be functionalized with immunoglobulins and functionalized nanoparticles exhibit flow properties in lateral-flow assay.
引用
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页码:2297 / 2300
页数:4
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